Compare Cancer Stem Cells in the Human Breast Cancer Cell Line with Those in the Primary Cells

作者: HE Yan-li , Tian Yuan , Liu Chun-ping , Li Zhi , Huang Tao

DOI:

关键词: Breast cancerCancerCancer stem cellCD44Somatic evolution in cancerInternal medicineMedicineCA 15-3OncologyCA15-3Stem cell

摘要: Objective To compare the content and phenotype of cancer stem cells in MCF-7,MDA-MB-231S human breast cell line with those primary cells.Methods Different subpopulation were detected separated from by flow cytometry,and their ability to reconstruct tumor was determined vivo.Results The expression distribution CD44 CD24 different.Compared cells,the proportion MCF-7 MDA-MB-231S higher(P 0.01).Conclusion Compared cells,there are more has been changed.

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