作者: HE Yan-li , Tian Yuan , Liu Chun-ping , Li Zhi , Huang Tao
DOI:
关键词: Breast cancer 、 Cancer 、 Cancer stem cell 、 CD44 、 Somatic evolution in cancer 、 Internal medicine 、 Medicine 、 CA 15-3 、 Oncology 、 CA15-3 、 Stem cell
摘要: Objective To compare the content and phenotype of cancer stem cells in MCF-7,MDA-MB-231S human breast cell line with those primary cells.Methods Different subpopulation were detected separated from by flow cytometry,and their ability to reconstruct tumor was determined vivo.Results The expression distribution CD44 CD24 different.Compared cells,the proportion MCF-7 MDA-MB-231S higher(P 0.01).Conclusion Compared cells,there are more has been changed.