Use of Ion Selective Microelectrodes to Measure Intracellular Free Mg2+

摘要: Mg2+ has been dubbed “the forgotten cation” (Brady et al. 1987) for although it is the second most common intracellular cation, study of its homeostasis and regulatory function in health disease long neglected. Gradually, however, becoming clear that plays an important role: It a co-factor numerous enzymatic reactions, on several ionic channels, influences Ca2+ uptake into mitochondria K+ by skeletal muscle, may play crucial role cardiovascular (see reviews Altura 1988; Elin Shils Lauter 1989; White Hartzeil Review Am J Med 1987).