Modeling cancer glycolysis.

作者: Alvaro Marín-Hernández , Juan Carlos Gallardo-Pérez , Sara Rodríguez-Enríquez , Rusely Encalada , Rafael Moreno-Sánchez

DOI: 10.1016/J.BBABIO.2010.11.006

关键词: HexokinaseBiologyGlucose transporterGlycogenBiochemistryBioenergeticsCancer cellGlyceraldehyde 3-phosphate dehydrogenasePhosphofructokinaseGlycolysis

摘要: … The accelerated glycolysis rate can provide the required glycolytic intermediary precursors for DNA, protein and lipid synthesis necessary to sustaining the active proliferation of tumor …

参考文章(64)
L.J. Reitzer, B.M. Wice, D. Kennell, The pentose cycle. Control and essential function in HeLa cell nucleic acid synthesis. Journal of Biological Chemistry. ,vol. 255, pp. 5616- 5626 ,(1980) , 10.1016/S0021-9258(19)70674-7
K Snell, G Weber, Enzymic imbalance in serine metabolism in rat hepatomas. Biochemical Journal. ,vol. 233, pp. 617- 620 ,(1986) , 10.1042/BJ2330617
Harold P. Morris, Peter C. Heinrich, George Weber, Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver. Cancer Research. ,vol. 36, pp. 3189- 3197 ,(1976)
Y Kashiwaya, K Sato, N Tsuchiya, S Thomas, D A Fell, R L Veech, J V Passonneau, Control of glucose utilization in working perfused rat heart. Journal of Biological Chemistry. ,vol. 269, pp. 25502- 25514 ,(1994) , 10.1016/S0021-9258(18)47278-X
Marco G. Paggi, Richard A. Nakashima, Laura J. Scott, Peter L. Pedersen, Purification and characterization of a bindable form of mitochondrial bound hexokinase from the highly glycolytic AS-30D rat hepatoma cell line. Cancer Research. ,vol. 48, pp. 913- 919 ,(1988)
Rafael Moreno-Sánchez, Rusely Encalada, Alvaro Marín-Hernández, Emma Saavedra, Experimental validation of metabolic pathway modeling. FEBS Journal. ,vol. 275, pp. 3454- 3469 ,(2008) , 10.1111/J.1742-4658.2008.06492.X
Alvaro Marín-Hernández, Sara Rodríguez-Enríquez, Paola A. Vital-González, Fanny L. Flores-Rodríguez, Marina Macías-Silva, Marcela Sosa-Garrocho, Rafael Moreno-Sánchez, Determining and understanding the control of glycolysis in fast‐growth tumor cells FEBS Journal. ,vol. 273, pp. 1975- 1988 ,(2006) , 10.1111/J.1742-4658.2006.05214.X
Hans Ulrich Bergmeyer, Methods of Enzymatic Analysis ,(1963)