[Predictive value of body mass index combined with waist circumference for new-onset nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus].

作者: Haitao Wang , Weihuan Zhang , Hongfen Liu , Jian Zhang , Ruixiu Zhang

DOI: 10.12122/J.ISSN.1673-4254.2019.11.05

关键词: Proportional hazards modelType 2 Diabetes MellitusBody mass indexCumulative incidenceCohort studyInternal medicineNonalcoholic fatty liver diseaseProspective cohort studyGastroenterologyWaistMedicine

摘要: Objective To investigate the predictive value of body mass index (BMI) combined with waist circumference (WC) for new-onset nonalcoholic fatty liver disease (NAFLD) in patients type 2 diabetes mellitus (T2DM). Methods This community-based prospective cohort study was conducted among 3501 T2DM without NAFLD recruited from staff Kailuan Company, who underwent routine physical examination year 2006 and 2007, a total 2920 subjects were included final analysis. According to baseline BMI WC, divided into group A (with normal WC), B but elevated C WC) D WC). The 4 groups followed occurrence by reviewing their reports examinations during periods 2008-2009, 2010-2011, 2012-2013, 2014-2015 2016-2017. cumulative incidence compared across Cox regression analysis used test correlation WC new onset NAFLD. Results increased progressively (50%, 66%, 68% 77%, respectively). showed that A, B, had risks after adjusting age, gender other risk factors, HR values 1.62, 1.98 2.47, respectively. Conclusions Elevated are both independent factors diabetic patients, combination has greater than either them alone.

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