Breast cancer incidence trends in European women aged 20-39 years at diagnosis

摘要: An increase in the incidence of breast cancer women aged<40 years has been reported recent years. Increased could be partly explained by subtle detection biases, but role other risk factors cannot ruled out. The purpose present study was to investigate changes temporal trends European aged 20-39 at diagnosis. Age specific rates for 17 Cancer Registries were retrieved calendar period 1995-2006. registries data pooled reduce annual fluctuations single and stability. Regression models fitted assuming that number cases followed Poisson distribution. Mean rate (AIC) across considered time window calculated. AIC estimated from all 1.032 (95% CI=1.019-1.045) 1.014 CI=1.010-1.018) 20-29 30-39 old diagnosis, respectively. major change detected among 25-29 diagnosis: AIC=1.033 CI=1.020-1.046). upward trend not affected when with high or low removed analysis (sensitivity analysis). Our findings support presence an their 20s 30s during decade interpretation observed is straightforward since a may have our results. result burden disease important terms public health deserves further investigation possible factors.