Perplexing Metabolomes in Fungal-Insect Trophic Interactions: A Terra Incognita of Mycobiocontrol Mechanisms

摘要: The trophic interactions of entomopathogenic fungi in different ecological niches viz., soil, plants, or insect themselves are effectively regulated by their maneuvered metabolomes and the plethora metabotypes. In this article, we discuss a holistic framework co-evolutionary metabotypes to model biocontrol especially with mycosed insects. Conventionally, studies involving fungal mechanisms reported context much aggrandized entomotoxins while adaptive response host insects relatively overlooked. present review asserts that selective pressure exerted among competing interacting species drives alterations overall which ultimately implicates corresponding Quintessentially, metabolomics offers most generic tractable assess fungal-insect antagonism terms interaction biomarkers, biosynthetic pathway plasticity, defense. chiefly rely on battery secondary metabolites falling categories NRP's (non-ribosomal peptides), PK's (polyketides), lysine derive alkaloids, terpenoids. On contrary, overcome mycosis through employing layers immunity manifested as altered (phenoloxidase activity) carbohydrates, lipids, fatty acids, amino eicosanoids. Here, recent findings within conventional premise entomotoxicity evolution truculent immune insect. metabolomic frameworks for can potentially transmogrify our current comprehensions develop hypervirulent strains least environmental concerns. Moreover, (interactome) complementation other -omics cascades could further be applied address fundamental bottlenecks co-evolution biological species.