The metabolism and anti-atherogenic properties of HDL

作者: Kerry-Anne Rye , Christina A. Bursill , Gilles Lambert , Fatiha Tabet , Philip J. Barter

DOI: 10.1194/JLR.R800034-JLR200

关键词: Anti atherogenicDisease riskMetabolismInflammationFunction (biology)BiologyCholesterol hdlPopulationCholesterolInternal medicineEndocrinology

摘要: Population studies have shown that plasma HDL levels correlate inversely with cardiovascular disease risk. In recent years there has been intense interest in developing strategies for exploiting these cardioprotective properties by increasing levels. While this approach considerable merit, it is important to recognize are structurally and functionally diverse consist of numerous, highly dynamic subpopulations particles do not all inhibit atherosclerosis the same extent. For reason essential assess subpopulation distribution functionality when considering therapeutic interventions raise This review documents what known about relationship between metabolism function how affects their properties.

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