作者: Kirk I. Erickson , Regina L. Leckie , Andrea M. Weinstein
DOI: 10.1016/J.NEUROBIOLAGING.2014.03.034
关键词: Neuroscience 、 Physical fitness 、 Gray (unit) 、 Brain size 、 Physical medicine and rehabilitation 、 Cognition 、 Cardiorespiratory fitness 、 Psychology 、 Exercise intervention 、 Physical activity 、 Prefrontal cortex
摘要: In this review, we explore the association among physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher fitness levels are routinely associated with greater prefrontal cortex hippocampus less consistently other regions. also activity is same regions including hippocampus. Some heterogeneity literature may be explained by effect moderation age, stress, or factors. Finally, report promising results from randomized interventions suggest of remain pliable responsive to moderate intensity for 6 months-1 year. Physical appears a propitious method influencing late adulthood, but additional well-controlled studies necessary inform public policies about potential protective therapeutic effects brain volume.