Physical activity, fitness, and gray matter volume.

作者: Kirk I. Erickson , Regina L. Leckie , Andrea M. Weinstein

DOI: 10.1016/J.NEUROBIOLAGING.2014.03.034

关键词: NeurosciencePhysical fitnessGray (unit)Brain sizePhysical medicine and rehabilitationCognitionCardiorespiratory fitnessPsychologyExercise interventionPhysical activityPrefrontal cortex

摘要: In this review, we explore the association among physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher fitness levels are routinely associated with greater prefrontal cortex hippocampus less consistently other regions. also activity is same regions including hippocampus. Some heterogeneity literature may be explained by effect moderation age, stress, or factors. Finally, report promising results from randomized interventions suggest of remain pliable responsive to moderate intensity for 6 months-1 year. Physical appears a propitious method influencing late adulthood, but additional well-controlled studies necessary inform public policies about potential protective therapeutic effects brain volume.

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