Ultra-sensitive SQUID instrumentation for MEG and NCI by ULF MRI

作者: Rainer Körber

DOI: 10.1007/978-981-10-5122-7_199

关键词: Instrumentation (computer programming)BiomagnetismPhysicsHybrid systemAcousticsCurrent density imagingElectromagnetic coilNoise (electronics)SquidSensitivity (control systems)

摘要: The requirements for the construction of ultra-sensitive SQUID instrumentation as used in biomagnetism are presented. Typically, SQUIDs inductively coupled to pick-up coils and this arrangement one can improve noise performance by increasing sensing coil area. To achieve optimum sensitivity has consider signal-to-noise ratio (SNR), which is an intricate interplay between source characteristics origin. It turns out that separate designs needed various even identical source. Hence, a hybrid system with differently sized presents best option multipurpose applications. A single channel close intrinsic level also described. This possible utilizing special dewar design thereby enabling further increase SNR. Such might be current density imaging neuronal ultra-low-field magnetic resonance where it must able field-tolerant up 100-200 mT.

参考文章(11)
Alex I. Braginski, John Clarke, Applications of SQUIDs and SQUID systems Wiley-VCH. ,(2006)
H.C. Seton, J.M.S. Hutchison, D.M. Bussell, Liquid helium cryostat for SQUID-based MRI receivers Cryogenics. ,vol. 45, pp. 348- 355 ,(2005) , 10.1016/J.CRYOGENICS.2004.11.011
A.I. Ahonen, M.S. Hamalainen, R.J. Ilmoniemi, M.J. Kajola, J.E.T. Knuutila, J.T. Simola, V.A. Vilkman, Sampling theory for neuromagnetic detector arrays IEEE Transactions on Biomedical Engineering. ,vol. 40, pp. 859- 869 ,(1993) , 10.1109/10.245606
Rainer Körber, Jaakko O. Nieminen, Nora Höfner, Vojko Jazbinšek, Hans-Jürgen Scheer, Kiwoong Kim, Martin Burghoff, An advanced phantom study assessing the feasibility of neuronal current imaging by ultra-low-field NMR. Journal of Magnetic Resonance. ,vol. 237, pp. 182- 190 ,(2013) , 10.1016/J.JMR.2013.10.011
Jukka Nenonen, Juha Montonen, Toiro Katila, Thermal Noise in Biomagnetic Measurements Review of Scientific Instruments. ,vol. 67, pp. 2397- 2405 ,(1996) , 10.1063/1.1147514
D.. Drung, C.. Assmann, J.. Beyer, A.. Kirste, M.. Peters, F.. Ruede, T.. Schurig, Highly Sensitive and Easy-to-Use SQUID Sensors IEEE Transactions on Applied Superconductivity. ,vol. 17, pp. 699- 704 ,(2007) , 10.1109/TASC.2007.897403
Martin Burghoff, Rainer Körber, Dietmar Drung, Jan-Hendrik Storm, A modular, extendible and field-tolerant multichannel vector magnetometer based on current sensor SQUIDs arXiv: Instrumentation and Detectors. ,(2017) , 10.1088/0953-2048/29/9/094001
John Clarke, Alex I Braginski, The SQUID handbook Wiley-VCH Verlag GmbH & Co. KGaA. ,(2006) , 10.1002/9783527609956
Rainer Körber, Jan-Hendrik Storm, Hugh Seton, Jyrki P Mäkelä, Ritva Paetau, Lauri Parkkonen, Christoph Pfeiffer, Bushra Riaz, Justin F Schneiderman, Hui Dong, Seong-min Hwang, Lixing You, Ben Inglis, John Clarke, Michelle A Espy, Risto J Ilmoniemi, Per E Magnelind, Andrei N Matlashov, Jaakko O Nieminen, Petr L Volegov, Koos CJ Zevenhoven, Nora Höfner, Martin Burghoff, Keiji Enpuku, SY Yang, Jen-Jei Chieh, Jukka Knuutila, Petteri Laine, Jukka Nenonen, None, SQUIDs in biomagnetism: a roadmap towards improved healthcare Superconductor Science and Technology. ,vol. 29, pp. 113001- ,(2016) , 10.1088/0953-2048/29/11/113001
Rainer Körber, Dietmar Drung, Jan-Hendrik Storm, Peter Hömmen, An ultra-sensitive and wideband magnetometer based on a superconducting quantum interference device Applied Physics Letters. ,vol. 110, pp. 072603- ,(2017) , 10.1063/1.4976823