Early cerebral infarction as a risk factor for poor outcome after aneurysmal subarachnoid haemorrhage.

摘要: Background and purpose:  After aneurysmal subarachnoid haemorrhage, severity of bleeding, occurrence rebleeding cerebral infarcts are the main factors predicting outcome. We investigated predictive risk for both early late infarcts, whether time appearance infarct is associated with outcome. Methods:  Previous diseases as well clinical, laboratory radiological variables including serial CT scans were recorded 173 patients admitted within 48 h after bleeding ruptured aneurysm occlusion by open surgery 60 h. Factors poor outcome at 3 months according to Glasgow Outcome Scale tested using multiple logistic regression. Results:  Of several potential predictors, was independently predicted patient age, rebleeding, intraventricular intracerebral haematoma, delayed ischaemia fixed symptoms new ischaemic lesion on scan appearing 1st post-operative morning (P < 0.01 each factor). adjustment confounding factors, (odds ratio 12.5; 95% confidence interval 3.2–48.7; P < 0.01), (6.6; 1.1–40.4; P < 0.05), only (2.4; 0.6–9.1) increased Adjusted independent significant infarction duration artery during (1.4/min; 1.1–1.7, P < 0.01) admission plasma glucose level (1.3 per mM; 1.0–1.6, P < 0.05) amount blood (4.5; 1.3–14.9, P < 0.05). Conclusion:  Early surgical seems have different worse prognosis than which mostly ischaemia.