The role of antioxidant vitamins and enzymes in the prevention of exercise-induced muscle damage.

摘要: A growing amount of evidence indicates that free radicals play an important role as mediators skeletal muscle damage and inflammation after strenuous exercise. It has been postulated the generation oxygen is increased during exercise a result increases in mitochondrial consumption electron transport flux, inducing lipid peroxidation. The literature suggests dietary antioxidants are able to detoxify peroxides produced exercise, which could otherwise peroxidation, they capable scavenging peroxyl therefore may prevent damage. Endogenous antioxidant enzymes also protective process studies reviewed (rodent human) show significant malondialdehyde (a product peroxidation) exhaustion, favourable changes plasma levels enzyme activity. In trained individuals rats, activity markedly. this way, oxidative stress induced by compromised activity, preventing Human have shown supplementation with vitamins effects on peroxidation Although several points discussion still exist, question whether exercise-induced can be answered affirmatively. human indicate vitamin recommended performing regular heavy Moreover, advantage compared untrained individuals, training results major overall status. However, future needed order give more specific information recommendations topic.