作者: Kenneth M. Shaw
DOI: 10.1016/J.METABOL.2006.02.001
关键词: Glycemic 、 Type 2 diabetes 、 Internal medicine 、 Type 2 Diabetes Mellitus 、 Hypoglycemia 、 Endocrine disease 、 Glimepiride 、 Diabetes mellitus 、 Medicine 、 Endocrinology 、 Gliclazide
摘要: Abstract Several factors influence diabetes control, and many of these can adversely affect endeavors to obtain optimal glycemic management. For patients with type 2 mellitus, the passage time often results in a loss responsiveness medication greater difficulty achieving desired target levels. Although observations part reflect natural progression diabetes, irrespective treatment given, it is possible identify modifiable hurdles that be addressed better outcome results. Lifestyle measures, particularly diet exercise, remain paramount, whereas other secondary confounding such as systemic or endocrine disease conflicting need specific therapeutic attention. Most mellitus will require oral hypoglycemic this should prescribed simplest, most effective, safest way. Ensuring fully understand objectives important resulting compliance advised treatment. Such significantly improved by keeping regimens simple. With its novel once-daily formulation, gliclazide modified release has been shown improve adherence result determined HbA 1c Its benefits terms reduced risk hypoglycemia have demonstrated GlUcose control In diabetes: Diamicron versus glimEpiride study.