The response of hypophysectomized male killifish (Fundulus heteroclitus) to thyrotropin preparations and to the bovine heterothyrotropic factor

摘要: Abstract The thyroid glands of hypophysectomized male Fundulus heteroclitus were stimulated by chronic administration bovine heterothyrotropic factor (HTF), purified stimulating hormone (TSH) and reference standard TSH-USP at doses 1 μg/gm, mU (0.07 μg)/gm, 0.1 mU/gm, respectively. Thyroid function was measured in four ways with similar results: cell height, I 131 uptake the area on day 2 (probe), 4 (well counter), serum butanol-extractable (BEI ). A relatively low-order response to HTF TSH appears be related absence some unknown pituitary that is present standard, but studies growth hematocrit showed it not somatotropin nor an erythrocyte-stimulating factor. slight stimulation regressed testes resulted from treatment TSH, TSH.