Conjugates of sodium channel blockers and methods of using the same
作者： Jr. Richard C. Boucher
DOI:
关键词: Receptor 、 Conjugate 、 Agonist 、 Chemistry 、 Sodium channel blocker 、 Pharmacology
摘要: Compounds of the general formula P1-L-P2; wherein 'P1' is a pyrazinoylguanidine sodium channel blocker, 'L' linking group, and 'P2' either (i) blocker or (ii) P2Y2 receptor agonist, are disclosed. Pharmaceutical formulations containing same methods use thereof to hydrate mucosal surfaces such as airway also
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