Antimicrobial resistance and its control in pediatrics

摘要: Abstract The scope and magnitude of antimicrobial resistance among nosocomial pathogens have increased dramatically in recent years. most prevalent problems pediatric patients are Enterobacter, Klebsiella, other gram-negative enteric bacilli resistant to broad-spectrum penicillins third-generation cephalosporins;methicillin-resistant coagulase-negative staphylococci; multidrug-resistant Pseudomonas aeruginosa. Methicillin-resistant Staphylococcus aureus vancomycin-resistant enterococci also important problems, but they still focal their distribution. Multiple factors affect the emergence, selection, amplification, dissemination determinants, not least which is incredible capacity bacteria spread genes coding for determinants within species. Inadequate infection control practices overuse agents modifiable factors. Improved use barrier precautions alcohol-based waterless hand rubs reduced been shown reduce or colonization with bacteria. However, more research—including randomized controlled trials—is needed devise strategies effectively combat this problem. Copyright © 2001 by W.B. Saunders Company