Membrane nanodomains in plants: capturing form, function, and movement

摘要: The plasma membrane is the interface between cell and external environment. Plasma lipids provide scaffolds for proteins protein complexes that are involved in to communication, signal transduction, immune responses, transport of small molecules. In animals, fungi, plants, a substantial subset these function within ordered sterol- sphingolipid-rich nanodomains. High-resolution microscopy, lipid dyes, pharmacological inhibitors biosynthesis, biosynthetic mutants have been employed examine relationship environment activity plants. They also used identify associated with nanodomains pathways by which nanodomain-associated trafficked their destinations. These studies suggest plant context-specific manner, analogous similar structures animals fungi. addition highly conserved flotillin remorin markers, some members B G subclasses ATP binding cassette transporters emerged as functional markers Further, glycophosphatidylinositol-anchored fasciclin-like arabinogalactan proteins, often detergent-resistant membranes, appear role