Evaluation of the need to discontinue antiplatelet and anticoagulant medications before cataract surgery

作者: Hiroshi Kobayashi

DOI: 10.1016/J.JCRS.2010.01.017

关键词: Cataract surgeryDiscontinuationMedicineIntraocular lensSubconjunctival hemorrhageWarfarinSurgeryAnesthesiaAspirinAnticoagulantPhacoemulsification

摘要: Purpose To assess the risk for intraoperative and postoperative bleeding associated with antiplatelet and/or anticoagulant treatment in patients having uneventful phacoemulsification. Setting Kokura Memorial Hospital, Kitakyusyu, Japan. Methods In a nonrandomized case series, consecutive had phacoemulsification intraocular lens implantation under sub-Tenon anesthesia. All were on warfarin, acetylsalicylic acid (aspirin) therapy, or both. Patients discontinued therapy 1 week before surgery (discontinuation group) continued therapeutic regimen until time of (maintenance group). Results The discontinuation group comprised 182 maintenance group, 173 patients. There was no significant difference between 2 groups mean prothrombin time–international normalized ratio taking warfarin ( P = .6). Although there any case, 47 eyes (16.5%) 31 (10.8%) subconjunctival hemorrhage postoperatively .0309). Minor ocular occurred 11 (4.0%) 7 (2.5%) .4). During 1-month period, change corrected distance visual acuity −0.462 logMAR ± 0.331 (SD) −0.434 0.318 .3). Conclusions aspirin, both up to significantly higher incidence than those who therapy. complications improvement. Financial Disclosure author has financial proprietary interest material method mentioned.

参考文章(17)
Kristin Carter, Kevin M. Miller, Phacoemulsification and lens implantation in patients treated with aspirin or warfarin Journal of Cataract and Refractive Surgery. ,vol. 24, pp. 1361- 1364 ,(1998) , 10.1016/S0886-3350(98)80229-0
J D Benzimra, , R L Johnston, P Jaycock, P H Galloway, G Lambert, A K K Chung, T Eke, J M Sparrow, The Cataract National Dataset electronic multicentre audit of 55,567 operations: antiplatelet and anticoagulant medications. Eye. ,vol. 23, pp. 10- 16 ,(2009) , 10.1038/SJ.EYE.6703069
Nishant Kumar, Sharmila Jivan, Peter Thomas, Hamish McLure, Sub-Tenon's anesthesia with aspirin, warfarin, and clopidogrel Journal of Cataract and Refractive Surgery. ,vol. 32, pp. 1022- 1025 ,(2006) , 10.1016/J.JCRS.2006.02.035
Chaiwat Teekhasaenee, Robert Ritch, The Use of PhEA 34c in Trabeculectomy Ophthalmology. ,vol. 93, pp. 487- 491 ,(1986) , 10.1016/S0161-6420(86)33720-5
Andrew S. Dunn, Alexander G. G. Turpie, Perioperative Management of Patients Receiving Oral Anticoagulants Archives of Internal Medicine. ,vol. 163, pp. 901- 908 ,(2003) , 10.1001/ARCHINTE.163.8.901
Steven P. Gainey, Dennis M. Robertson, William Fay, Duane Ilstrup, Ocular surgery on patients receiving long-term warfarin therapy. American Journal of Ophthalmology. ,vol. 108, pp. 142- 146 ,(1989) , 10.1016/0002-9394(89)90008-1
Ainsley Morris, Mark J Elder, Warfarin therapy and cataract surgery. Clinical and Experimental Ophthalmology. ,vol. 28, pp. 419- 422 ,(2000) , 10.1046/J.1442-9071.2000.00350.X