Excimer laser with adjunctive balloon angioplasty and heparin-coated self-expanding stent grafts for the treatment of femoropopliteal artery in-stent restenosis: twelve-month results from the SALVAGE study.

摘要: Objectives: The aim of the study is to evaluate safety and effectiveness treating femoropopliteal in-stent restenosis (ISR) with debulking excimer laser followed by implantation a VIABAHN endoprosthesis. Background: optimal treatment strategy for ISR unclear. Methods: SALVAGE multicenter prospective registry involving nine US centers. Patients moderate severe intermittent claudication or critical limb ischemia (Rutherford categories 2–5) an ankle-brachial index (ABI) =0.8 were treated primary efficacy endpoint patency at 12 months as measured duplex ultrasonography. major adverse event (MAE) rate 30 days. Results: Twenty-seven patients enrolled. mean lesion length was 20.7 6 10.3 cm. majority lesions TASC (TASC I) C D (81.4%). All pretreated percutaneous transluminal angioplasty (PTA) prior implantation. Technical success achieved in 100% cases. There no MAE Primary 48%. ankle brachial increased from 0.58 0.24 baseline 0.90 0.17 months. improvement all quality-of-life parameters. 12-month TLR 17.4%. Conclusions: atherectomy PTA self-expanding stent graft safe associated high procedural success. 12-months suboptimal; however, low. V 2012 Wiley Periodicals, Inc.