作者: ELIZABETH ARTHUR , C. M. STEEL , H. J. EVANS , SUSAN POVEY , B. WATSON
DOI: 10.1038/257308A0
关键词: Genetic analysis 、 Genetics 、 Biology 、 Lymphoblastoid cell 、 Structural gene 、 Somatic cell 、 Line (text file) 、 Structural locus 、 Lymphoblast 、 Induced mutation
摘要: LONG term genetic analysis of lymphoblastoid cell lines provides a practical means studying the types spontaneous and induced mutation that can occur in human somatic cells1,2 following evolution distinct populations cells within bulk culture3,4. Occasionally, data may be expected to emerge which facilitate localisation structural genes. We now report first such application this technique.