Familial hypercholesterolaemia in primary care: knowledge and practices among general practitioners in Western Australia.

作者: Damon A. Bell , Jacquie Garton-Smith , Alistair Vickery , Andrew B. Kirke , Jing Pang

DOI: 10.1016/J.HLC.2013.08.005

关键词: Health professionalsCommunity modelPrimary careCholesterol lowering drugsFamily medicineManagement practicesLipid profilePediatricsMedicineCholesterol loweringLaboratory reports

摘要: Aim To determine general practitioners’ (GPs’) knowledge and practice regarding familial hypercholesterolaemia (FH) in Western Australia. Method A structured questionnaire was anonymously completed by GPs. Information sought on awareness of FH including, diagnosis, inheritance, prevalence, cardiovascular risk, management practices opinions screening. Results 191 GPs the survey, 62% were familiar with FH, 80% correctly defined 68% identified typical lipid profile, but only 33% aware national guidelines. There deficits clinical features correct responses 27%, 45% 38%, respectively. Most (84%) considered themselves most effective health professionals to detect 90% preferring laboratory interpretative commenting highlight individuals at risk FH. appropriate cholesterol lowering drugs as mono (95%) or combination therapies (74%). Conclusion The majority they practitioners for managing preferred reports alert them possible Although good, their guidelines, hereditability, prevalence diagnostic suboptimal. Implementing a community model care requires more extensive GP education.

参考文章(22)
Leon A Simons, Graham Levis, Judith Simons, Apparent discontinuation rates in patients prescribed lipid-lowering drugs. The Medical Journal of Australia. ,vol. 164, pp. 208- 211 ,(1996) , 10.5694/J.1326-5377.1996.TB94138.X
Gordon Calcino, Michael Ortiz, Leon A Simons, Long term persistence with statin therapy -- experience in Australia 2006-2010. Australian Family Physician. ,vol. 40, pp. 319- 322 ,(2011)
Michael J McKay, None, Family history: the neglected risk factor in disease prevention The Medical Journal of Australia. ,vol. 193, pp. 429- 430 ,(2010) , 10.5694/J.1326-5377.2010.TB03983.X
Robert Bender, Damon A. Bell, Amanda J. Hooper, Glenn Edwards, Frank M. van Bockxmeer, Gerald F. Watts, John R. Burnett, Screening for familial hypercholesterolaemia Pathology. ,vol. 44, pp. 122- 128 ,(2012) , 10.1097/PAT.0B013E32834EFA07
Marianne Benn, Gerald F. Watts, Anne Tybjaerg-Hansen, Børge G. Nordestgaard, Familial Hypercholesterolemia in the Danish General Population: Prevalence, Coronary Artery Disease, and Cholesterol-Lowering Medication The Journal of Clinical Endocrinology and Metabolism. ,vol. 97, pp. 3956- 3964 ,(2012) , 10.1210/JC.2012-1563
Amanda J. Hooper, Lan T. Nguyen, John R. Burnett, Timothy R. Bates, Damon A. Bell, Trevor G. Redgrave, Gerald F. Watts, Frank M. van Bockxmeer, Genetic analysis of familial hypercholesterolaemia in Western Australia Atherosclerosis. ,vol. 224, pp. 430- 434 ,(2012) , 10.1016/J.ATHEROSCLEROSIS.2012.07.030
Gerald F Watts, Amanda Juniper, Frank van Bockxmeer, Zanfina Ademi, Danny Liew, Peter OʼLeary, Familial hypercholesterolaemia: a review with emphasis on evidence for treatment, new models of care and health economic evaluations International Journal of Evidence-based Healthcare. ,vol. 10, pp. 211- 221 ,(2012) , 10.1111/J.1744-1609.2012.00272.X
Nadeem Qureshi, Steve E Humphries, Mary Seed, Philip Rowlands, Rubin Minhas, , Identification and management of familial hypercholesterolaemia: what does it mean to primary care? British Journal of General Practice. ,vol. 59, pp. 773- 778 ,(2009) , 10.3399/BJGP09X472674
Gerald F. Watts, David R Sullivan, Nicola Poplawski, Frank van Bockxmeer, Ian Hamilton-Craig, Peter M. Clifton, Richard O’Brien, Warrick Bishop, Peter George, Phillip J. Barter, Timothy Bates, John R. Burnett, John Coakley, Patricia Davidson, Jon Emery, Andrew Martin, Waleed Farid, Lucinda Freeman, Elizabeth Geelhoed, Amanda Juniper, Alexa Kidd, Karam Kostner, Ines Krass, Michael Livingston, Suzy Maxwell, Peter O’Leary, Amal Owaimrin, Trevor G. Redgrave, Nicola Reid, Lynda Southwell, Graeme Suthers, Andrew Tonkin, Simon Towler, Ronald Trent, Familial hypercholesterolaemia: a model of care for Australasia. Atherosclerosis Supplements. ,vol. 12, pp. 221- 263 ,(2011) , 10.1016/J.ATHEROSCLEROSISSUP.2011.06.001
Dalya Marks, Margaret Thorogood, H.Andrew W Neil, Steve E Humphries, A review on the diagnosis, natural history, and treatment of familial hypercholesterolaemia. Atherosclerosis. ,vol. 168, pp. 1- 14 ,(2003) , 10.1016/S0021-9150(02)00330-1