Novel approach for synthesis of catechins
作者： Sundeep Dugar , Dinesh Mahajan , Ishwar Rakesh Patil , Kumar Santosh Rai , Vinayak Tripathi
DOI:
关键词: Racemic mixture 、 Organic chemistry 、 Quercetin 、 Reducing agent 、 Chemistry
摘要: A process for synthesis of enatiomerically pure or enriched racemic mixture (+and/or-) epicatechin and its intermediates, comprising the steps of: (i) obtaining penta-protected quercetin; (ii) reducing quercetin obtained from step (i); (iii) optionally deprotecting compound (ii); (iv) in presence a chiral/achiral agent to obtain chiral intermediate; (v) and/or hydrogenation intermediate (-)-epicatechin; (vi) simultaneously epicatechin.
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