Fibrinogen metabolism and disseminated intravascular coagulation in dengue hemorrhagic fever.

摘要: In 29 patients with dengue hemorrhagic fever (DHF), 12 grade 2 and 17 grades 3 4, fibrinogen metabolism was studied by using 125I-fibrinogen; 11 of these were during shock. Hemostatic studies also performed to search for evidence disseminated intravascular coagulation (DIC). Increased coagulation, as judged rapid T1/2 125I-fibrinogen, well DIC hemostatic DHF had only 17% DIC. Of the shock, 91% both DIC, whereas 63% 18 without shock 11% this latter group A correlation between increased consumption clinical severity, demonstrated. The role in pathogenesis is discussed, heparin suggested prolonged severe acidosis when becomes clinically apparent.