A critical review of the in vitro and in vivo models for the evaluation of anti-infective meshes

作者: O. Guillaume , B. Pérez Kohler , R. Fortelny , H. Redl , F. Moriarty

DOI: 10.1007/S10029-018-1807-Z

关键词: Animal modelStandardizationAbdominal wall repairMedicineEmerging technologiesRisk analysis (engineering)SurgeryAnti infectivesPolygon meshHernia repair

摘要: Infectious complications following mesh implantation for abdominal wall repair appear in 0.7 up to 26.6% of hernia repairs and can have a detrimental impact the patient. To prevent or treat mesh-related infection, scientific community is currently developing veritable arsenal antibacterial meshes. The numerous increasing reports published every year describing new technologies indicate clear clinical need, an academic interest solving this problem. Nevertheless, really appreciate, challenge, compare optimize properties next generation meshes, it important know which models are available understand them. We proposed first time, complete overview focusing only on vitro vivo been employed specifically field meshes repair. From investigation, that there has vast progress breadth test However, also shows standardization adoption more restricted number would improve comparability be benefit study.

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