Isolation and characterization of isoforms of HspBP1, inhibitors of Hsp70.

作者: Deborah A Raynes , Vince Guerriero

DOI: 10.1016/S0167-4781(99)00238-9

关键词: Protein GMolecular biologyBiochemistryHSPA12ADNA-binding proteinGene isoformHsp70SNAP23ChemistryComplementary DNAAmino acid

摘要: The protein sequences derived from cDNA for Hsp70 binding proteins human (HspBP2) and rat tissues (HspBPR) are presented in this paper. amino acid of these differ HspBP1 the number consecutive glycines near amino-terminus. These differences, however, do not alter inhibitory activity.

参考文章(21)
Judith Frydman, Jörg Höhfeld, Chaperones get in touch: the Hip-Hop connection. Trends in Biochemical Sciences. ,vol. 22, pp. 87- 92 ,(1997) , 10.1016/S0968-0004(97)01005-0
S. Karlin, S. F. Altschul, Applications and statistics for multiple high-scoring segments in molecular sequences. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 5873- 5877 ,(1993) , 10.1073/PNAS.90.12.5873
Janice E. A. Braun, Sigurd M. Wilbanks, Richard H. Scheller, The Cysteine String Secretory Vesicle Protein Activates Hsc70 ATPase Journal of Biological Chemistry. ,vol. 271, pp. 25989- 25993 ,(1996) , 10.1074/JBC.271.42.25989
Pamela A. Silver, Jeffrey C. Way, Eukaryotic DnaJ homologs and the specificity of Hsp70 activity Cell. ,vol. 74, pp. 5- 6 ,(1993) , 10.1016/0092-8674(93)90287-Z
Shiying Chen, David F. Smith, Hop as an Adaptor in the Heat Shock Protein 70 (Hsp70) and Hsp90 Chaperone Machinery Journal of Biological Chemistry. ,vol. 273, pp. 35194- 35200 ,(1998) , 10.1074/JBC.273.52.35194
Douglas M Cyr, Thomas Langer, Michael G Douglas, None, DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70 Trends in Biochemical Sciences. ,vol. 19, pp. 176- 181 ,(1994) , 10.1016/0968-0004(94)90281-X
Shinichi Takayama, David N Bimston, Shu-ichi Matsuzawa, Brian C Freeman, Christine Aime-Sempe, Zhihua Xie, Richard I Morimoto, John C Reed, BAG‐1 modulates the chaperone activity of Hsp70/Hsc70 The EMBO Journal. ,vol. 16, pp. 4887- 4896 ,(1997) , 10.1093/EMBOJ/16.16.4887