The relationship between respiratory syncytial virus infections and the development of wheezing and asthma in children

摘要: Purpose of review The relationship between respiratory syncytial virus lower-respiratory-tract infections in early childhood and asthma has been the subject much debate. Most, but not all, previous cohort studies have failed to identify a link infection atopic asthma. Recent helped clarify some apparently contradictory findings. findings Cohort focusing on wheezing indicated that this is associated with an increased incidence risk by infection. Indeed, wheeze rhinovirus may be better marker for possible In contrast, there no disease infants ‘acute bronchiolitis’, phenotype characterized widespread crepitation. Post-bronchiolitic symptoms are intercurrent viral particular falls rapidly during infancy. Summary These confirm earlier suggestions illness hence host response rather than infecting organism best predictor future pattern illness. Such considerations must central design any intervention or studies.