Asthma and depression: the Cooper Center Longitudinal Study

作者: Timothy D. Trojan , David A. Khan , Laura F. DeFina , Oviea Akpotaire , Renee D. Goodwin

DOI: 10.1016/J.ANAI.2014.02.015

关键词: AsthmaMedicineInternal medicineDepression (differential diagnoses)SpirometryPsychiatryOdds ratioHistory of depressionCross-sectional studyCenter for Epidemiologic Studies Depression ScaleLongitudinal study

摘要: Abstract Background Prior research suggests a possible association between asthma and depression. Objective To examine the depressive symptoms, controlling for medications, lung function, overall health. Methods We conducted cross-sectional study of 12,944 adults who completed physician-based preventive health examinations at Cooper Clinic from 2000 to 2012. Information on medical histories, including depression, medications were collected. Participants reported status, spirometry testing, underwent depression screening using 10-item Center Epidemiologic Studies Depression Scale (CES-D). Dependent variables current symptoms (CES-D scores ≥10) lifetime history separately modeled logistic regression with independent variables, demographics, spirometry, controller patient-reported status. Results The sample was predominantly white well educated. prevalence 9.0%. Asthma associated an odds ratio (OR) 1.41 (95% CI, 1.16-1.70; P Conclusion increased in large relatively healthy adults. These findings suggest that likelihood among patients does not appear be exclusively related severe or poorly controlled asthma. People asthma, regardless severity, may benefit clinical settings.

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