Effect of tumor-specific KRAS mutational status on impact of anti-EGFR therapy in non-small cell lung cancer (NSCLC).

作者: M. C. Garassino , M. Marabese , M. Broggini , C. Lauricella , I. Floriani

DOI: 10.1200/JCO.2010.28.15_SUPPL.7564

关键词: OncologyMedicineTumor specificMutational statusMAPK/ERK pathwayInternal medicineKRASnon-small cell lung cancer (NSCLC)Cancer

摘要: 7564 Background: The RAS/RAF/MEK/ERK pathway is a therapeutic target in both colorectal (CRC) and NSCLC cancer, but while mutated KRAS negative prognostic marker predictor for a...

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