Endoscopic correction of vesicoureteral reflux in children using polyacrylate-polyalcohol copolymer (Vantris): 5-years of prospective follow-up.

摘要: Introduction The endoscopic correction of vesicoureteral reflux (VUR) in children is a currently well accepted therapy many pediatric urology centers. Polyacrylate-polyalcohol copolymer (PPC), namely Vantris®, one the tissue-augmenting substances used for therapy. aim this study was to evaluate results with PPC children. Material and methods From 2012 2016, 125 (73 girls 52 boys) aged 0.6-17.9 years (mean 4.9 ±3.58) were treated PPC. VUR unilateral 64 bilateral 61 patients, comprising 197 renal refluxing units (RRUs) grades: II 72, III 50, IV 33 V 42. Of these primary present 132 RRUs 65 complex cases. Voiding cystourethrogram (VCUG) done 3 months after procedure. Results Follow-up completed 89.6% patients (112 children), 89.8% (177 out 197). Reflux resolved 86.4% single injection, 99.4% second 100% third. only significant, but serious complication observed late ureteral obstruction injection correcting high grade reflux, which required re-implantation. This found 9 112 (8%), 11 177 (6.2%), 1.1 -2.9 2 ±0.7) injection. longest follow-up reaches 4.5 years. Conclusions Our data show that an effective procedure treating all grades success rate. However, because possibility obstruction, requires ureteroneocystostomy, long-term mandatory.