Outcomes in elderly patients with newly diagnosed and treated epilepsy.

摘要: Epilepsy develops most commonly in the elderly. Seizures can severely affect a senior citizen's quality of life, and despite growing elderly population with epilepsy, there is paucity good clinical data this age group. To address some issues encountered by patients prospective information from attending Unit at Western Infirmary Glasgow, Scotland, was analyzed. Ninety patients, aged 65-93 years, were diagnosed epilepsy started on antiepileptic drug (AED) treatment. Neuroimaging performed 84 (93%), 69 evaluated via computerized tomography 15 magnetic resonance imaging; abnormalities found 45 (54%). Sixty-eight underwent interictal electroencephalography, which revealed epileptiform discharges 18 (26%). Fifty-eight 90 (64%) became seizure free for least 12 months modest doses first prescribed AED. remained uncontrolled 21 (23%), AED withdrawn 11 (12%) because adverse events. Following pharmacological manipulation, total 76 (84%) achieved freedom. Patients starting treatment > or =2 years after their less likely to achieve control than who initiated earlier. Newly more remain newly younger populations (p < 0.001). The majority had partial-onset seizures, underlying cerebral atrophy infarcts common. Treating an older person initial therapy be complicated; taking adequate time communicating clearly are paramount. Although positive outcome, all AEDs have disadvantages population. Choice may depend comorbidity comedication, among other factors. Initial dosing should low slow titration schedule. A holistic approach care helps optimize outcome people epilepsy.