Hashimoto Thyroiditis in Childhood – Review of the Epidemiology, Genetic Susceptibility and Clinical Aspects of the Disease

摘要: Chronic autoimmune thyroiditis or Hashimoto’s (HT) is the most common cause of thyroid diseases in children and adolescents. It also acquired hypothyroidism with without goiter. The incidence has increased dramatically over past few decades, affecting up to 5% general population iodine sufficient areas. HT caused by complex interplay genetic, environmental, endogenous factors. Significant progress been made identifying characterizing genes involved pathogenesis disease. aim this review analyze current opinions options regarding etiology, genetic contribution pathogenesis, evaluation, diagnosis, treatment, prognosis children.