The Role of Hydrogen Sulfide in Evolution and the Evolution of Hydrogen Sulfide in Metabolism and Signaling

作者: Kenneth R. Olson , Karl D. Straub

DOI: 10.1152/PHYSIOL.00024.2015

关键词: BiologySulfideAstrobiologyHydrogen sulfideHydrogen sulfide metabolismSulfurEcologyAmbient oxygenEnergy sourceMetabolismAbiogenesis

摘要: The chemical versatility of sulfur and its abundance in the prebiotic Earth as reduced sulfide (H2S) implicate this molecule origin life 3.8 billion years ago also a major source energy first seven-eighths evolution. tremendous increase ambient oxygen ∼ 600 million brought an end to H2S source, H2S-dependent animals either became extinct, retreated isolated niches, or adapted. 3 molecular tinkering were not lost, however, much biochemical armamentarium easily adapted oxic environment where it contributes metabolism signaling even humans. This review examines role evolution signaling.

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