Sensitization of rhabdo-, lenti-, and spumaviruses to human serum by galactosyl(alpha1-3)galactosylation.
作者： Y Takeuchi , S H Liong , P D Bieniasz , U Jäger , C D Porter
DOI: 10.1128/JVI.71.8.6174-6178.1997
关键词: Vesicular stomatitis Indiana virus 、 Biology 、 Virus 、 Vesicular stomatitis virus 、 Antibody 、 Human foamy virus 、 Genetic enhancement 、 Spumavirus 、 Viral envelope 、 Virology
摘要: Vesicular stomatitis virus, human immunodeficiency virus type 2, and foamy which were produced by cell lines expressing galactosyl(alpha1-3)galactosyl (alphaGal) sugars, found to be less stable in serum than those from alphaGal-negative cells, indicating that galactosyl(alpha1-3)galactosylation sensitizes these viruses as well mammalian C oncoviruses (Rother et al., J. Exp. Med. 182:1345-1355, 1995; Takeuchi Nature (London) 379:85-88, 1996) complement killing via natural anti-alphaGal antibodies. Thus, mediated antibodies may play a role barrier animal-to-human infection of various enveloped viruses. Virus vectors for vivo gene therapy based on the mentioned above should cells.
sci-hub.st 参考文章(33)
U Galili, F Anaraki, A Thall, C Hill-Black, M Radic, One percent of human circulating B lymphocytes are capable of producing the natural anti-Gal antibody Blood. ,vol. 82, pp. 2485- 2493 ,(1993) , 10.1182/BLOOD.V82.8.2485.2485
Robert D Larsen, CA Rivera-Marrero, LK Ernst, RD Cummings, JB Lowe, None, Frameshift and nonsense mutations in a human genomic sequence homologous to a murine UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase cDNA. Journal of Biological Chemistry. ,vol. 265, pp. 7055- 7061 ,(1990) , 10.1016/S0021-9258(19)39258-0
U Galili, S B Shohet, E Kobrin, C L Stults, B A Macher, Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells. Journal of Biological Chemistry. ,vol. 263, pp. 17755- 17762 ,(1988) , 10.1016/S0021-9258(19)77900-9
D W Russell, A D Miller, Foamy virus vectors. Journal of Virology. ,vol. 70, pp. 217- 222 ,(1996) , 10.1128/JVI.70.1.217-222.1996
F L Cosset, Y Takeuchi, J L Battini, R A Weiss, M K Collins, High-titer packaging cells producing recombinant retroviruses resistant to human serum. Journal of Virology. ,vol. 69, pp. 7430- 7436 ,(1995) , 10.1128/JVI.69.12.7430-7436.1995
B Maurer, H Bannert, G Darai, R M Flügel, Analysis of the primary structure of the long terminal repeat and the gag and pol genes of the human spumaretrovirus. Journal of Virology. ,vol. 62, pp. 1590- 1597 ,(1988) , 10.1128/JVI.62.5.1590-1597.1988
J K Rose, C J Gallione, Nucleotide sequences of the mRNA's encoding the vesicular stomatitis virus G and M proteins determined from cDNA clones containing the complete coding regions. Journal of Virology. ,vol. 39, pp. 519- 528 ,(1981) , 10.1128/JVI.39.2.519-528.1981
Y Takeuchi, F L Cosset, P J Lachmann, H Okada, R A Weiss, M K Collins, Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell. Journal of Virology. ,vol. 68, pp. 8001- 8007 ,(1994) , 10.1128/JVI.68.12.8001-8007.1994
J J Hooks, C J Gibbs, The foamy viruses. Bacteriological Reviews. ,vol. 39, pp. 169- 185 ,(1975) , 10.1128/BR.39.3.169-185.1975
Yasuhiro Takeuchi, Colin D. Porter, Karen M. Strahan, Andrew F. Preece, Kenth Gustafsson, Francois-Loic Cosset, Robin A. Weiss, Mary K. L. Collins, Sensitization of cells and retroviruses to human serum by (αl-3) galactosyltransferase Nature. ,vol. 379, pp. 85- 88 ,(1996) , 10.1038/379085A0