The crown-gall potato disk bioassay as a primary screen for compounds with antitumor activity.

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DOI: 10.1093/JNCI/67.3.689

关键词: Primary (chemistry)LeukemiaEthanol extractsP388 leukemiaPlant TumorsChemistryBioassayBotanyAntitumor activityGallBiochemistry

摘要: A variety of samples consisting purified compounds (of various origins) and ethanol extracts from plants were assayed for their activity on the growth initiation crown-gall tumors potato disks. The results demonstrated a high correlation between ability these to inhibit disks corresponding mouse P388 leukemia protocol. Of 21 tested date, there two false-positives one false-negative.

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