Mapping of human and macaque sensorimotor areas by integrating architectonic, transmitter receptor, MRI and PET data.

摘要: The human and macaque sensorimotor cortex was subdivided into numerous areas by a correlative analysis based on cytoarchitectonics, myeloarchitecture the distribution of transmitter receptors. Receptor densities laminar patterns differ not only between motor somatosensory regions, but also different within these regions cortex. Changes in receptor often match architectonically defined borders. findings provide new criteria for more detailed mapping brain which cannot be achieved cytoarchitectonic alone. Morphological data were integrated with functional from positron emission tomography (PET) basis recently developed computerised atlas. central sulcus marks border (1) agranular generally low density glutamatergic, muscarinic, GABAergic serotoninergic receptors, (2) granular higher Rostral to primary cortex, 2 isocortical are found mesial probably represent functionally supplementary (SMA) SMA-proper (caudally) pre-SMA (rostrally). Below 24d (macaque) caudal cingulate area cmc (human) located sulcus. Both correspond 'posterior areas' recent PET studies posterior part architectonic studies. 24c rostral cmr sulcus; they 'anterior observations anterior Homologous can both species common features.