Risk of hospitalisation with coronavirus disease 2019 in healthcare workers and their households: a nationwide linkage cohort study

作者: Anoop SV Shah , Rachael Wood , Ciara Gribben , David Caldwell , Jennifer Bishop

DOI: 10.1101/2020.08.03.20164897

关键词: Absolute risk reductionHealth careHazard ratioComorbidityCohort studyIntensive careCohortEnvironmental healthPopulationMedicine

摘要: Abstract Objective Many healthcare staff work in high-risk settings for contracting and transmitting Severe Acute Respiratory Syndrome Coronavirus 2. Their risk of hospitalisation coronavirus disease 2019 (COVID-19), that their households, is poorly understood. Design participants During the peak period COVID-19 infection Scotland (1st March 2020 to 6th June 2020) we conducted a national record linkage study compare among workers (age: 18-65 years), households other members general population. Main outcome Hospitalisation with Results The cohort comprised 158,445 workers, majority being patient facing (90,733 / 158,445; 57.3%), 229,905 household members. Of all hospitalisations working age population (18-65-year-old), 17.2% (360 2,097) were or households. Adjusting age, sex, ethnicity, socio-economic deprivation comorbidity, non-patient was similar (hazards ratio [HR] 0.81; 95%CI 0.52-1.26 0.86; 0.49-1.51 respectively). In models adjusting same covariates however, compared at higher (HR 3.30; 2.13-5.13); so too 1.79; 1.10-2.91). On sub-dividing patient-facing into those who worked front-door, intensive care non-intensive aerosol generating other, ‘front door’ roles 2.09; 1.49-2.94). For most estimated absolute less than 0.5% but 1% above older men comorbidity. Conclusions Healthcare contribute sixth hospitalised cases. Whilst low overall, had 3- 2-fold increased risks hospitalisation.

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