Retinal degeneration in cats fed casein. I. Taurine deficiency.

摘要: All cats fed a taurine-free casein diet for at least 23 weeks have shown granularity with hyper-reflective white zone in the area centralis, nondetectable electroretinograms (ERG's), and structural changes indicating photoreceptor cell degeneration. The present study has demonstrated that this selective decrease plasma retinal taurine concentrations by five weeks; levels were about 4 per cent of normal plasma, 60 retina. After 10 weeks, 2 to reached minimum 20 30 These biochemical occurred association delay cone ERG implicit time reduced rod amplitudes weeks. During period, DNA content (as measure viability) fundus appearance normal. By ERG's nondetectable, was reduced, showed typical centralis. studies help establish biological role maintaining function viability cat.