Antibiotic resistance profiles of Pseudomonas aeruginosa isolated from various Greek aquatic environments.

作者: Pappa Olga , Vantarakis Apostolos , Galanis Alexis , Vantarakis George , Mavridou Athena

DOI: 10.1093/FEMSEC/FIW042

关键词: AztreonamCefotaximeMeropenemIntegronCeftazidimePseudomonas aeruginosaAntibiotic resistanceMicrobiologyAntibioticsBiology

摘要: A large number of antibiotic-resistant P. aeruginosa isolates are continuously discharged into natural water basins mainly through sewage. However, the environmental reservoirs antibiotic resistance factors poorly understood. In this study, patterns 245 from various aquatic sites in Greece were analysed. Twenty-three with cefotaxime-aztreonam-ceftazidime, cefotaxime-aztreonam-meropenem, cefotaxime-ceftazidime-meropenem, cefotaxime-ceftazidime-aztreonam-meropenem and cefotaxime-ceftazidime-cefepime-aztreonam-meropenem screened phenotypically for presence extended spectrum β-lactamases (ESBLs), while 77 resistant phenotypes class 1 2 integrase genes. The aztreonam-resistant ESBL producers main all habitats tested. 13/77 integron was detected, tested negative gene. CTX-M group 9 β-lactamase present a small (three isolates) highlighting emergence genes environments. As conclusion, it seems that Greek bodies could serve as potential reservoir posing threats to human animal health.

参考文章(62)
E. Amaya, D. Reyes, M. Paniagua, S. Calderón, M.-U. Rashid, P. Colque, I. Kühn, R. Möllby, A. Weintraub, C.E. Nord, Antibiotic resistance patterns of Escherichia coli isolates from different aquatic environmental sources in Leon, Nicaragua Clinical Microbiology and Infection. ,vol. 18, ,(2012) , 10.1111/J.1469-0691.2012.03930.X
S.G. Pereira, J. Paixão, R. Leitão, O. Cardoso, Pseudomonas aeruginosa in a hydropathic facility: diversity, susceptibility and imipenem resistance mutation Letters in Applied Microbiology. ,vol. 53, pp. 518- 524 ,(2011) , 10.1111/J.1472-765X.2011.03139.X
N. Mesaros, P. Nordmann, P. Plésiat, M. Roussel-Delvallez, J. Van Eldere, Y. Glupczynski, Y. Van Laethem, F. Jacobs, P. Lebecque, A. Malfroot, P.M. Tulkens, F. Van Bambeke, Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium. Clinical Microbiology and Infection. ,vol. 13, pp. 560- 578 ,(2007) , 10.1111/J.1469-0691.2007.01681.X
N.B. Hirulkar Hirulkar, “Incidence of Antibiotic-Resistant Pseudomonas aeruginosa Isolated from Drinking Water” International Journal of Pharmaceutical & Biological Archive. ,vol. 2, ,(2011)
Anna Marron, Jordi Carratalà, Fernando Alcaide, Alberto Fernández-Sevilla, Francesc Gudiol, High rates of resistance to cephalosporins among viridans-group streptococci causing bacteraemia in neutropenic cancer patients Journal of Antimicrobial Chemotherapy. ,vol. 47, pp. 87- 91 ,(2001) , 10.1093/JAC/47.1.87
Junying Ma, Jian-Hua Liu, Luchao Lv, Zhiyong Zong, Yan Sun, Hongqing Zheng, ZhangLiu Chen, Zhen-Ling Zeng, Characterization of Extended-Spectrum β-Lactamase Genes Found among Escherichia coli Isolates from Duck and Environmental Samples Obtained on a Duck Farm Applied and Environmental Microbiology. ,vol. 78, pp. 3668- 3673 ,(2012) , 10.1128/AEM.07507-11
David Sánchez, Margarita Gomila, Antonio Bennasar, Jorge Lalucat, Elena García-Valdés, Genome Analysis of Environmental and Clinical P. aeruginosa Isolates from Sequence Type-1146 PLoS ONE. ,vol. 9, pp. e107754- ,(2014) , 10.1371/JOURNAL.PONE.0107754
Céline Slekovec, Julie Plantin, Pascal Cholley, Michelle Thouverez, Daniel Talon, Xavier Bertrand, Didier Hocquet, Tracking down antibiotic-resistant Pseudomonas aeruginosa isolates in a wastewater network. PLOS ONE. ,vol. 7, ,(2012) , 10.1371/JOURNAL.PONE.0049300
Aysegul Copur Cicek, Aysegul Saral, Azer Ozad Duzgun, Zeynep Cizmeci, Tuba Kayman, Pervin Ozlem Balci, Tuba Dal, Mehmet Firat, Yelda Yazici, Metin Sancaktar, Osman Birol Ozgumus, Cemal Sandalli, Screening of Class 1 and Class 2 Integrons in Clinical Isolates of Pseudomonas aeruginosa Collected from Seven Hospitals in Turkey: A Multicenter Study Open Journal of Medical Microbiology. ,vol. 03, pp. 227- 233 ,(2013) , 10.4236/OJMM.2013.34034