Ex-vivo normothermic perfusion in renal transplantation

摘要: PURPOSE OF REVIEW Marginal donor kidneys make up a substantial proportion of transplanted kidneys. Nonetheless, they are more susceptible to injury during procurement and preservation. Normothermic perfusion is an alternative method organ preservation that can be used improve the quality, resuscitate, assess potentially repair organ. This review provides up-to-date summary role normothermic in renal transplantation what we expect future. RECENT FINDINGS has been demonstrated feasible well tolerated series extended criteria Furthermore, as quality assessment tool for pretransplant. In future, could manipulate using gene stem cell therapies ameliorating function after injury. SUMMARY last 5 years, translated from experimental laboratory technique into clinical practice with promising results. itself multifaceted its application transplantation. It may early graft kidney before The implications these applications crucial maximizing use organs available perpetual climate shortage.