Different granule cell populations innervate superficial and deep regions of the external plexiform layer in rat olfactory bulb

摘要: Studies on the morphological organization of main olfactory bulb have indicated that there are subpopulations granule cells with different dendritic patterns in external plexiform layer (EPL). Small, extracellular injections horseradish peroxidase (HRP) were made iontophoretically into superficial and deep parts EPL cell (GCL) adult rats. Superficial principally labeled somata, whereas both somata. Injections GCL processes extending across entire EPL. However, few dendrites EPL, but many such These results same material processed Hanker-Yates procedure, where morphology individual neurons could be studied, more sensitive tetramethyl benzidineprocedure. Serial reconstructions from HRP Golgi-Kopsch material. The distal reached only as far they branched extensively had spines. cells, however, most part ramified extensively. typically a higher spine density than part. On basis these results, we conclude predominantly innervate exclusively Granule believed to exert inhibitory influences bulbar output neurons, mitral tufted through reciprocal dendrodendritic synapses. Since secondary ramify may preferentially modulate responses respectively.