Epithelial to mesenchymal transition and breast cancer.

作者: Eva Tomaskovic-Crook , Erik W Thompson , Jean Paul Thiery

DOI: 10.1186/BCR2416

关键词: OncologyEpigeneticsBreast carcinomaInternal medicineCancer stem cellEpithelial–mesenchymal transitionPrimary tumorMetastasisBreast cancerBiologyCancer

摘要: … During carcinoma progression, epithelial cells detach from the … epithelial cells from primary tumors closely resembles that of cells undergoing EMT followed by mesenchymal to epithelial …

参考文章(90)
Andrea Rosner, Keiko Miyoshi, Esther Landesman-Bollag, Xin Xu, David C. Seldin, Amy R. Moser, Carol L. MacLeod, G. Shyamala, Amy E. Gillgrass, Robert D. Cardiff, Pathway pathology: Histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors American Journal of Pathology. ,vol. 161, pp. 1087- 1097 ,(2002) , 10.1016/S0002-9440(10)64269-1
Grit Kasper, Matthias Reule, Miriam Tschirschmann, Niels Dankert, Karen Stout-Weider, Roland Lauster, Evelin Schrock, Detlev Mennerich, Georg N Duda, Kerstin E Lehmann, Stromelysin-3 over-expression enhances tumourigenesis in MCF-7 and MDA-MB-231 breast cancer cell lines: involvement of the IGF-1 signalling pathway. BMC Cancer. ,vol. 7, pp. 12- 12 ,(2007) , 10.1186/1471-2407-7-12
C. A. Schoenenberger, A. C. Andres, B. Groner, M. van der Valk, M. LeMeur, P. Gerlinger, Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription. The EMBO Journal. ,vol. 7, pp. 169- 175 ,(1988) , 10.1002/J.1460-2075.1988.TB02797.X
Anne Vincent-Salomon, Jean Paul Thiery, Host microenvironment in breast cancer development: Epithelial–mesenchymal transition in breast cancer development Breast Cancer Research. ,vol. 5, pp. 101- 106 ,(2003) , 10.1186/BCR578
R. Poulsom, P. Anglard, I. Hart, D. Barnes, E. Dublin, A. Hanby, A. Ahmad, R. Rubens, P. Smith, Stromelysin 3: an independent prognostic factor for relapse-free survival in node-positive breast cancer and demonstration of novel breast carcinoma cell expression. American Journal of Pathology. ,vol. 152, pp. 721- 728 ,(1998)
Kian-Ngiap Chua, Jing Ma, Jean-Paul Thiery, Targeted therapies in control of EMT in carcinoma and fibrosis Drug Discovery Today: Disease Mechanisms. ,vol. 4, pp. 261- 267 ,(2007) , 10.1016/J.DDMEC.2008.06.002
G Moreno-Bueno, F Portillo, A Cano, Transcriptional regulation of cell polarity in EMT and cancer. Oncogene. ,vol. 27, pp. 6958- 6969 ,(2008) , 10.1038/ONC.2008.346
Maria J Blanco, Gema Moreno-Bueno, David Sarrio, Annamaria Locascio, Amparo Cano, José Palacios, M Angela Nieto, None, Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene. ,vol. 21, pp. 3241- 3246 ,(2002) , 10.1038/SJ.ONC.1205416
Philip A. Gregory, Andrew G. Bert, Emily L. Paterson, Simon C. Barry, Anna Tsykin, Gelareh Farshid, Mathew A. Vadas, Yeesim Khew-Goodall, Gregory J. Goodall, The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 Nature Cell Biology. ,vol. 10, pp. 593- 601 ,(2008) , 10.1038/NCB1722
Mark Shackleton, François Vaillant, Kaylene J. Simpson, John Stingl, Gordon K. Smyth, Marie-Liesse Asselin-Labat, Li Wu, Geoffrey J. Lindeman, Jane E. Visvader, Generation of a functional mammary gland from a single stem cell Nature. ,vol. 439, pp. 84- 88 ,(2006) , 10.1038/NATURE04372