Germacrane-Type Sesquiterpenes from Curcuma wenyujin

作者: Yan Lou , Feng Zhao , Zhaohua Wu , Kai‐Feng Peng , Xing‐Chuan Wei

DOI: 10.1002/HLCA.200900059

关键词: SesquiterpeneChemistryStereochemistryLactamMedicinal plantsOrganic chemistryPlant compositionCurcuma wenyujinChemical structure

摘要: Two new germacrane-type sesquiterpene lactones, curdionolides A and B (1 2, resp.), a novel lactam, curdionolide C (3), were isolated from Curcuma wenyujin. Y. H. Chen et C. Ling together with five known sesquiterpenes, 4–8. The structures of the compounds elucidated by spectroscopic methods. inhibitory effects 1–8 on nitric oxide (NO) production in lipopolysaccharide-activated macrophages evaluated.

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