Tat as an immunogen

作者: Russell J. Mumper , Zhengrong Cui , Avindra Nath , Jerold G. Woodward

DOI:

关键词: ImmunogenVaccinationVirologyBacterial RNABiologyHuman immunodeficiency virus (HIV)Hiv 1 tatRecombinant DNA

摘要: Non-denatured, recombinant human immunodeficiency virus (HIV) Tat that is free of bacterial RNA and endotoxin employed in an anti-HIV vaccine. A process producing the protein includes steps for removing from protein. Tat-adsorbed nanoparticle formulation method making same. vaccinating against and/or treating HIV infection comprises administering to a subject need such vaccination or treatment immune­response inducing effective amount