Genetic alterations and DNA repair in human carcinogenesis
作者： Kathleen Dixon , Elizabeth Kopras
DOI: 10.1016/J.SEMCANCER.2004.06.007
关键词: Carcinogenesis 、 Mutagenesis 、 Biology 、 Genetics 、 DNA repair 、 DNA damage 、 Cancer epigenetics 、 DNA mismatch repair 、 Epigenetics 、 DNA replication
摘要: A causal association between genetic alterations and cancer is supported by extensive experimental and epidemiological data. Mutational inactivation of tumor suppressor genes …
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