Multi-spectral laser imaging (MSLI) methods and systems for blood flow and perfusion imaging and quantification

摘要: Some embodiments of the present inventive concept provide a system that uses two wavelengths differential transmittance through sample to apply laser speckle or Doppler imaging. A first is within visible range has zero very shallow penetration. This wavelength captures anatomical structure tissue/organ surface and serves as position marker but not subsurface movement blood flow perfusion. second in near Infra-Red (NIR) range, which much deeper reveals underlying physiology correlates both motion also Thus, true perfusion can be derived from NIR imaging measurement without being affected by artifact target.