Hydroxyl free radical is not the main active species in site-specific DNA damage induced by copper (II) ion and hydrogen peroxide.

作者： K Yamamoto , S Kawanishi

DOI: 10.1016/S0021-9258(19)84847-0

关键词: Adduct 、 Singlet oxygen 、 Thymine 、 Hydrogen peroxide 、 Photochemistry 、 DNA damage 、 Hydroxyl radical 、 Free radical damage to DNA 、 Guanine 、 Chemistry

摘要: … In this study, we examined site specificity of Cu(I1)-induced DNA cleavage in the presence of H202 by using 32P 5’ endlabeled DNA fragments of defined sequence and investigated …

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