Coexpression, coregulation, and cofunctionality of neighboring genes in eukaryotic genomes.
作者： Pawel Michalak
DOI: 10.1016/J.YGENO.2007.11.002
关键词: Regulation of gene expression 、 Computational biology 、 Saccharomyces cerevisiae 、 Gene 、 Genome 、 Gene expression 、 Genomics 、 Biology 、 Operon 、 Gene cluster 、 Genetics
摘要: Accumulating evidence indicates that gene order in eukaryotic genomes is not completely random and genes with similar expression levels tend to be clustered within the same genomic neighborhoods. The mechanism behind these coexpression clusters as yet unclear. In this article, plausible biochemical, genetic, evolutionary, technological determinants of pattern are briefly reviewed.
core.ac.uk
elsevier.com
sci-hub.se 参考文章(80)
Richard E Davis, Scott Hodgson, Gene linkage and steady state RNAs suggest trans-splicing may be associated with a polycistronic transcript in Schistosoma mansoni Molecular and Biochemical Parasitology. ,vol. 89, pp. 25- 39 ,(1997) , 10.1016/S0166-6851(97)00097-2
Jan H Vogel, Anja von Heydebreck, Antje Purmann, Silke Sperling, Chromosomal clustering of a human transcriptome reveals regulatory background BMC Bioinformatics. ,vol. 6, pp. 230- 230 ,(2005) , 10.1186/1471-2105-6-230
Paul T Spellman, Gerald M Rubin, Evidence for large domains of similarly expressed genes in the Drosophila genome. Journal of Biology. ,vol. 1, pp. 5- 5 ,(2002) , 10.1186/1475-4924-1-5
Helene H Thygesen, Aeilko H Zwinderman, Modelling the correlation between the activities of adjacent genes in drosophila BMC Bioinformatics. ,vol. 6, pp. 10- 10 ,(2005) , 10.1186/1471-2105-6-10
Hui Ge, Zhihua Liu, George M. Church, Marc Vidal, Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae Nature Genetics. ,vol. 29, pp. 482- 486 ,(2001) , 10.1038/NG776
Dominic J Allocco, Isaac S Kohane, Atul J Butte, Quantifying the relationship between co-expression, co-regulation and gene function BMC Bioinformatics. ,vol. 5, pp. 18- 18 ,(2004) , 10.1186/1471-2105-5-18
Sven Nelander, Erik Larsson, Erik Kristiansson, Robert Månsson, Olle Nerman, Mikael Sigvardsson, Petter Mostad, Per Lindahl, Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals BMC Genomics. ,vol. 6, pp. 68- 68 ,(2005) , 10.1186/1471-2164-6-68
T.R. Hebbes, A.L. Clayton, A.W. Thorne, C. Crane-Robinson, Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain. The EMBO Journal. ,vol. 13, pp. 1823- 1830 ,(1994) , 10.1002/J.1460-2075.1994.TB06451.X
Brian Oliver, Michael Parisi, David Clark, Gene expression neighborhoods Journal of Biology. ,vol. 1, pp. 4- 4 ,(2002) , 10.1186/1475-4924-1-4
John Merakovsky, Leonard E. Kelly, Michiko Smith, Justen Andrews, Frances Hannan, Michelle Coulson, The stoned locus of Drosophila melanogaster produces a dicistronic transcript and encodes two distinct polypeptides. Genetics. ,vol. 143, pp. 1699- 1711 ,(1996) , 10.1093/GENETICS/143.4.1699