Identification of Factors Affecting the Success of Next-Generation Sequencing Testing in Solid Tumors.

作者: Rashmi S. Goswami , Rajyalakshmi Luthra , Rajesh R. Singh , Keyur P. Patel , Mark J. Routbort

DOI: 10.1093/AJCP/AQV023

关键词: DNA sequencingParaffin BlockSample qualityHotspot mutationMinimally invasive proceduresOncologyIon semiconductor sequencingResectionBioinformaticsBiologyTumor typeInternal medicine

摘要: Objectives: Clinical laboratories are rapidly implementing next-generation sequencing (NGS) tests for mutation analysis, but there are few guidelines regarding sample quality for …

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