Immunohistochemical study of jejunal graft mucosa cell populations during the initial adaptation phase in the host body in rats

摘要: Abstract The character of the changes in cell populations within jejunal graft mucosa during initial adaptation phase host body was investigated. 24 adult male Wistar rats underwent intestinal heterotopic allotransplantation. Aorto-aortal and porto-caval anastomoses were performed using end-to-side microsurgery technique. Graft tissues compared to recipients. This study demonstrates that: (1) Distinct injury 1 h after transplantation accompanied by significant reduction numbers epithelial secretory populations. more intense mesenteric portion. Six hours covered a continuous epithelium, but number goblet Paneth cells found be less than 30% that recipient epithelium. (2) In comparison with recipients, myeloperoxidase-positive increased significantly transplantation. layer, denudation destruction villi associated intraepithelial lymphocyte numbers. A decrease mucosal mast detected 6 h They attained only 10% (3) Time-dependent revealed CD163-positive reached level contrast, population decreased 6 h.