Studies on the regulation of cholesterol metabolism by low‐and high‐density lipoproteins in HepG2 cellsx
作者： Subramanian Ranganathan , Bruce A. Kottke
关键词: Cholesterol metabolism 、 Cholesterol 、 High density 、 Intermediate-density lipoprotein 、 Blood lipids 、 Efflux 、 Acyl-CoA 、 Biochemistry 、 Chemistry 、 Reverse cholesterol transport
摘要: The uptake and degradation of low-density lipoproteins the esterification synthesis cholesterol were poorly down-regulated by in HepG2 cells. Addition to cells increased free esterified heavier fraction high-density enhanced decreased acyl CoA:cholesterol acyltransferase activity. also caused a net efflux from lighter did not have any significant effect on metabolism or cellular level. Neither nor fractions found specific binding properties
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