Antileishmanial, Antimicrobial and Antifungal Activities of Some New Aryl Azomethines
作者： Yasser M.S.A. Al-Kahraman , Hassan. M.F. Madkour , Dildar Ali , Masoom Yasinzai
DOI: 10.3390/MOLECULES15020660
关键词: Aryl 、 Molecular conformation 、 Chemical structure 、 Antibacterial activity 、 In vitro 、 Antimicrobial 、 Chemistry 、 Antifungal 、 Leishmania major 、 Organic chemistry
摘要: A series of eighteen azomethines has been synthesized by the reaction appropriate primary aromatic amines with aryl and/or heteroaryl carboxaldehydes. The have evaluated for their in vitro antileishmanial, antibacterial and antifungal activities. results revealed some activity most compounds, whereas antileishmaniasis highlighted that all inhibited parasite growth them showed highly potent action towards Leishmania major promastigotes. No remarkable bactericidal activities were observed.
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